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selenocysteine biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
ATP + L-serine + tRNASec <=> AMP + diphosphate + L-seryl-tRNASec 6.1.1.11 serine---tRNA ligase

S-methyl-L-methionine + L-selenocysteine <=> Se-methyl-L-selenocysteine + L-methionine + H+ 2.1.1
2.1.1.280 selenocysteine Se-methyltransferase


H2O + selenium + ATP <=> Selenophosphate + phosphate + AMP 2.7.9.3 selenide, water dikinase

O-phospho-L-seryl-tRNASec + Selenophosphate + H2O <=> L-Selenocysteinyl-tRNASec + 2 phosphate 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase

L-selenocysteine + reduced_acceptor <=> L-alanine + selenium + acceptor + H+ 4.4.1.16 selenocysteine lyase

ATP + L-seryl-tRNASec <=> ADP + O-phospho-L-seryl-tRNASec 2.7.1.164 O-phosphoseryl-tRNASec kinase

L-seryl-tRNASec + Selenophosphate <=> L-Selenocysteinyl-tRNASec + phosphate 2.9.1.1 L-seryl-tRNASec selenium transferase

Visualization of the pathway